In this case, you can delete all the content in the system and reinstall Firefox to fix Firefox won’t open Windows 10. Files can get corrupted or damaged by themselves and nothing you can do about it. Corrupted Files:Though it is not 100% sure, all the signs point towards corrupted files.You may raise a question “why not Firefox open”. Many Mozilla Firefox users complain that Firefox will not open even they double click the icon and run the browser as administrator. Possible Causes of Firefox Won’t Open Error Solution 2: Remove Logitech Cam Drivers.